Proteína C reactiva ultrasensible y perfil lipídico posterior a dieta hipocalórica en sujetos obesos

Jorly Mejía-Montilla; Nadia Reyna-Villasmil; Eduardo Reyna-Villasmil; Andreina Fernández-Ramírez; Pedro Herrera-Moya

doi:10.29076/issn.2528-7737vol13iss32.2020pp123-130p

Jorly Mejía-Montilla Universidad del Zulia
Nadia Reyna-Villasmil Universidad del Zulia
Eduardo Reyna-Villasmil Hospital Central Dr. Urquinaona
Andreina Fernández-Ramírez Facultad de Humanidades de La Universidad del Zulia. Maracaibo, Venezuela.
Pedro Herrera-Moya Universidad Estatal de Milagro

DOI: https://doi.org/10.29076/issn.2528-7737vol13iss32.2020pp123-130p

Palabras clave: Proteína C reactiva ultrasensible, Perfil lipídico, Obesidad, dieta de pérdida de peso.

Resumen

El objetivo del estudio fue comparar los cambios de las concentraciones de proteína C reactiva ultrasensible y perfil lipídico posterior a dieta hipocalórica en sujetos obesos. Fueron incluidos 105 sujetos adultos atendidos en el Hospital Universitario de Maracaibo, Venezuela. Los sujetos fueron instruidos para seguir una dieta hipocalórica durante 12 semanas. Se evaluaron variables antropométricas, concentraciones de proteína C reactiva ultrasensible y perfil lipídico. Se observaron disminuciones significativas en los valores de índice de masa corporal, circunferencia de cintura y proteína C reactiva ultrasensible después del programa de dieta hipocalórica para la pérdida de peso comparado con los valores iniciales (p < 0,05). Se observó disminución significativa de las concentraciones séricas de colesterol total y triglicéridos, después del programa (p = 0,039 y p = 0,028, respectivamente). Las concentraciones séricas de lipoproteínas de baja densidad y alta densidad disminuyeron luego del programa de dieta, pero las diferencias no fueron significativas (p = 0,229 y p = 0,142, respectivamente). Se concluye que las concentraciones de proteína C reactiva ultrasensible, colesterol y triglicéridos disminuyen en forma significativa en sujetos obesos luego de la implementación de un programa de dieta hipocalórica para la pérdida de peso.

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