ECOFARMACOVIGILANCIA AND THE DETERMINATION OF DICLOFENAC SODIUM BY ELECTROANALYSIS
Abstract
Diclofenac has become a drug widely consumed by patients due to its anti-inflammatory pharmacological action, which decreases the effect of prostaglandins, which cause inflammation and pain. Due to its inadequate final disposition, it causes ecological problems around the world, specifically in wildlife. Being part of the group of emerging pollutants, which are not regulated, despite the toxic effect capable of altering the biosphere, for example, the extinction of Asian vultures, the 100% mortality of zebrafish embryos at concentrations (100mg / L) with 70% of similarity to the human genome. This research raised the determination of diclofenac sodium in aqueous solutions using electroanalytic linear scanning (LSV). A vitreous carbon-screen modified carbon nanotube (WMCNT / SGCE) electrode containing an integrated auxiliary (platinum electrode) and a reference electrode (silver-silver chloride Ag / AgCl electrode) electrode were used. The pH study covered a range of potential from 0.25 V to 0.95 V, obtaining a better electrochemical development in acidic media. Calibration curves were constructed from commercial tablets and a DCF standard (USP). The linearity, accuracy, precision of the method were significant.Downloads
References
Afkhami, A., Bahiraei, A., & Madrakian, T. (2016). Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium. Materials Science and Engineering: C, 59, 168-176.
Alcántara Montero, A., & Sánchez Carnerero, C. I. (2016). Antiinflamatorios no esteroideos y riesgo de insuficiencia cardiaca: nuevas aportaciones. Revista de La Sociedad Española Del Dolor, 25(5), 306–307. https://doi.org/10.20986/resed.2016.3518/2016.
Alshakka, M., Mohamed Ibrahim, M. I., Hassali, M. A., Palaian, S., & Aljadhey, H. (2016). Hazards of Pharmaceuticals in Water as New Area in Eco-Pharmacovigilance Research. Journal of Pharmacy Practice and Community Medicine, 2(1), 03–08. https://doi.org/10.5530/jppcm.2016.1.2
Andrade Guel, M. L., López López, L. I., & Sáenz Galindo, A. (2012). Nanotubos de carbono: Funcionalización y aplicaciones biológicas. Revista Mexicana de Ciencias Farmacéuticas, 43(3), 9–18.
Bhuyian, M. H. U., Rashid, M. H. A., Islam, A. F. M. A., & Tareque, I. (2015). Development and validation of method for determination of clobetasol propionate and salicylic acid from pharmaceutical dosage form by HPLC. Br. J. Pharm. Res, 7, 375-385.
Bujes,J. (2013). “Estudio De Sensores Electroquímicos. Química Avanzada Especialidad En Nuevos Materiales.
Bolaños, K. L., Nagles, E., Arancibia, V., Otiniano, M., Leiva, Y., Mariño, A., & Scarpetta, L. (2014). Optimización de la técnica de voltamperometría de adsorción (Adsv) en la determinación de amaranth sobre electrodos serigrafiados de carbono: Efecto de surfactantes en la sensibilidad. Revista de la Sociedad Química del Perú, 80(2), 115-123.
Cano Paniagua, A., Cifuentes Posada, L. M., & Amariles Muñoz, P. J. (2017). Toxicidad hepática causada por medicamentos: revisión estucturada. Revista Colombiana de Gastroenterología, 32(4), 337. https://doi.org/10.22516/25007440.177.
Castro-Pastrana, L. I., Baños-Medina, M. I., Argelia López-Luna, M., & Torres-García, B. L. (2015). Ecofarmacovigilancia en México: perspectivas para su implementación Ecopharmacovigilance in Mexico: prospects of its implementation. Rev Mex Cienc Farm, 46(3). Retrieved from http://www.redalyc.org/pdf/579/57945705003.pdf.
Chamjangali, M. A., Kouhestani, H., Masdarolomoor, F., & Daneshinejad, H. (2015). A voltammetric sensor based on the glassy carbon electrode modified with multi-walled carbon nanotube/poly (pyrocatechol violet)/bismuth film for determination of cadmium and lead as environmental pollutants. Sensors and Actuators B: Chemical, 216, 384-393.
Ensafi, A. A., Izadi, M., & Karimi-Maleh, H. (2013). Sensitive voltammetric determination of diclofenac using room-temperature ionic liquid-modified carbon nanotubes paste electrode. Ionics, 19(1), 137–144. https://doi.org/10.1007/s11581-012-0705-0.
Garay Rairán, F. S., & Camargo Casallas, L. H. (2017). Avances en electrodos y biosensores elaborados con nanotubos de carbono Advances in electrodes and biosensors made from carbon nanotubes. Revista Científica Ingeniería Y Desarrollo, 36(1), 240–258. https://doi.org/10.14482/inde.36.1.10950.
Gómez, S., Biedma, G., Soria, E., & Vivo, M. (2002). Análisis Electroquímico. Revista de Diagnostico Biologico, 18-27.
Goyal, R. N., Chatterjee, S., & Rana, A. R. S. (2010). The effect of modifying an edge-plane pyrolytic graphite electrode with single-wall carbon nanotubes on its use for sensing diclofenac. Carbon, 48(14), 4136–4144. https://doi.org/10.1016/j.carbon.2010.07.024.
He, B. S., Wang, J., Liu, J., & Hu, X. M. (2017). Eco-pharmacovigilance of non-steroidal anti-inflammatory drugs: Necessity and opportunities. Chemosphere, 181, 178-189. Conocimientos y practicas.
Holm, G., & Snape, J. R. (2013). Implementing Ecopharmacovigilance in Practice : Challenges and Potential Opportunities, 533–546. https://doi.org/10.1007/s40264-013-0049-3.
Kalambate, P. K., & Srivastava, A. K. (2016). Simultaneous voltammetric determination of paracetamol, cetirizine and phenylephrine using a multiwalled carbon nanotube-platinum nanoparticles nanocomposite modified carbon paste electrode. Sensors and Actuators B: Chemical, 233, 237-248.
Lanas, A., Benito, P., Alonso, J., Hernández-Cruz, B., Barón-Esquivias, G., Perez-Aísa, Á., … Gonzalez-Juanatey, J. R. (2014). Recomendaciones para una prescripción segura de antiinflamatorios no esteroideos: Documento de consenso elaborado por expertos nominados por 3 sociedades científicas (SER-SEC-AEG). Gastroenterologia Y Hepatologia, 37(3), 107–127. https://doi.org/10.1016/j.gastrohep.2013.11.014.
Lindon, A. (2017). Diclofenaco En Buitres: ¿Podría Provocar El Declive De La Población Española? Revista Complutense de Ciencias Veterinarias, 11(especial), 253–258. https://doi.org/10.5209/RCCV.55682.
Loera, M. A. De, Hugo, S., Rodríguez, S., Lucila, I., Armando, J., Torre, F., & López-luna, A. (2016). Ecofarmacovigilancia. Rev.CENIC.Ciencias Biològicas, 47(1), 12–16.
Marcén, B., Sostres, C., & Lanas, A. (2016). Atención Primaria EDITORIAL AINE y riesgo digestivo NSAID and gastrointestinal risk. Atención Primaria, 48(2), 73–76. https://doi.org/10.1016/j.aprim.2015.04.008.
Martínez, M; Oliván, L; Chávez, A; Estrada, A; Medina, S. (2009). Evaluación de la toxicidad producida por diclofenaco adicionado al agua sobre Daphnia magna (Tesis de pregrado). Escuela Nacional de Ciencias Biologicas, Mexico.
Medhi, B., & Sewal, R. (2012). Ecopharmacovigilance: An issue urgently to be addressed. Indian Journal of Pharmacology, 44(5), 547. https://doi.org/10.4103/0253-7613.100363
Miranda, L., Felsner, M. L., Torres, Y. R., Hoss, I., Galli, A., & Quináia, S. P. (2015). In-House Validation of Methyltestosterone Determination in Natural Waters by Voltammetry Using Hanging Mercury Drop Electrode. Química Nova, 38(3), 419-426.
Quijano-Prieto, D. M., Orozco-Díaz, J. G., & Holguín-Hernández, E. (2016). Patients’ knowledge and practices about unconsumed drugs disposal: An approach to ecopharmacovigilance [Conocimientos y prácticas de pacientes sobre disposición de medicamentos no consumidos: Aproximación a la ecofarmacovigilancia]. Revista de Salud Publica, 18(1), 61–71. https://doi.org/10.15446/rsap.v18n1.44262.
Restrepo Giraldo, C. eduardo. (2015). Efecto del Diclofenaco sodico sobre la fisiología reproductiva de Daphnia pulex. Environmental Toxicology and Chemistry (ENVIRON TOXICOL CHEM). https://doi.org/10.13140/RG.2.1.3038.7367.
Sandoval, A. E. L., Colmenares, J. M. G., & Acuña, S. P. C. (2015). Validación del método voltamétrico para la determinación de residuos de paraquat aplicado en cultivos de papa. Acta Agronómica, 64(4), 336-341.
Scarpetta, L., Mariño, A., Bolaños, K., Leiva, Y., Castiblanco, P., & Nagles, É. (2015). Determination of hydroquinone using a glassy carbon electrode modified with chitosan, multi-wall carbon nano-tubes and ionic liquid. Possible use as sensor. Revista Colombiana de Ciencias Químico-Farmacéuticas, 44(3), 311-321.
Xia, Y., Si, J., & Li, Z. (2016). Fabrication techniques for microfluidic paper-based analytical devices and their applications for biological testing: A review. Biosensors and Bioelectronics, 77, 774-789.
Zavaleta-Espejo, G., Saldaña-Jiménez, J., Blas-Cerdán, W., & Meléndez–Rodríguez, D. (2018). Efecto del Diclofenaco sobre la fecundación de Tetrapygus niger “erizo negro de mar.” Rebiol, 38(1), 73–83.
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