Construction of growth patterns using the LMS model for Ecuadorian children and adolescents aged 5 to 18 years
DOI:
https://doi.org/10.29076/issn.2602-8360vol10iss18.2026pp118-129pKeywords:
children, adolescents, height, weight, growth curves, LMS method, Ecuador, growth referencesAbstract
Growth curves are a useful graphical tool for evaluating the growth patterns of groups of children and individuals. The objective of this study was to develop appropriate growth reference curves for Ecuadorian children and adolescents. The data for this cross-sectional study were collected from the database of the National Institute of Statistics and Census of Ecuador (INEC), including 20,532 healthy subjects (10,209 girls and 10,323 boys) from multiple cities and areas (urban and rural) of the country. Smoothed percentile curves were estimated using the LMS method for height (cm) and weight (kg). Smoothed percentile curves for height and weight increase with age in both sexes. Girls have an earlier peak pubertal velocity (10–12 years), while boys show it between 12 and 14 years. At age 14, boys' height values significantly exceed those of girls. This study showed discrepancies for certain age groups when comparing median height and weight values with those of the WHO, NCHS, and Colombian references, with Ecuadorian children and adolescents consistently lower than these references, especially from age 10 onwards. The maximum difference with the WHO reference reaches −10.2 cm in boys and −9.7 cm in girls at age 18. The smoothed percentile curves for height and weight will be useful for assessing the overall growth of Ecuadorian children and adolescents, and should be adopted in national pediatric clinical practice to replace international references that systematically overestimate the prevalence of growth disorders in this population.
Downloads
References
1. Debeko DD, Goshu AT. Height growth modeling in Ethiopian children and adolescents aged 7-20 years: A prospective cohort study. Biomed Res Int. 2025;2025(1):7288345. http://dx.doi.org/10.1155/bmri/7288345
2. de Onis M, Onyango A, Borghi E, Siyam A, Blössner M, Lutter C, et al. Worldwide implementation of the WHO Child Growth Standards. Public Health Nutr. 2012;15(9):1603–10. http://dx.doi.org/10.1017/S136898001200105X
3. Ghouili H, Ben Khalifa W, Ouerghi N, Zouaoui M, Dridi A, Gmada N, et al. Body mass index reference curves for Tunisian children. Arch Pediatr. 2018;25(8):459–63. http://dx.doi.org/10.1016/j.arcped.2018.09.005
4. Cole TJ. The development of growth references and growth charts. Ann Hum Biol. 2012;39(5):382–94. http://dx.doi.org/10.3109/03014460.2012.694475
5. Quamme SH, Iversen PO. Prevalence of child stunting in Sub-Saharan Africa and its risk factors. Clin Nutr Open Sci. 2022;42:49–61. http://dx.doi.org/10.1016/j.nutos.2022.01.009
6. Tanner JM, Whitehouse RH, Takaishi M. Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. I. Arch Dis Child. 1966;41(219):454–71. http://dx.doi.org/10.1136/adc.41.219.454
7. Hamill P, Drizd TA, Johnson CL, Reed RB, Roche AF. NCHS growth curves for children birth-18 years, United States. Vital Health Stat 11. 1977; (165):i-iv.1–74
8. WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards based on length/height, weight and age. Acta Paediatr Suppl. 2006;450:76–85. http://dx.doi.org/10.1111/j.1651-2227.2006.tb02378.x
9. de Onis M, Onyango AW, Borghi E, Siyam A, Nishida C, Siekmann J. Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ. 2007;85(9):660–7. http://dx.doi.org/10.2471/blt.07.043497
10. Kuczmarski RJ, Ogden CL, Guo SS, Grummer-Strawn LM, Flegal KM, Mei Z, et al. 2000 CDC Growth Charts for the United States: methods and development. Vital Health Stat 11. 2002;(246):1–190.
11. Marume A, Archary M, Mahomed S. Validation of growth standards and growth references: A review of literature. J Child Health Care. 2022;26(3):498–510. http://dx.doi.org/10.1177/13674935211024816
12. Ghouili H, Ouerghi N, Boughalmi A, Dridi A, Rhibi F, Bouassida A. First growth reference curves for Tunisian children and adolescents. Arch Pediatr. 2021;28(5):381–91. http://dx.doi.org/10.1016/j.arcped.2021.03.011
13. Asif M, Aslam M, Mazhar I, Ali H, Ismail T, Matłosz P, et al. Establishing height-for-age Z-score growth reference curves and stunting prevalence in children and adolescents in Pakistan. Int J Environ Res Public Health. 2022;19(19):12630. http://dx.doi.org/10.3390/ijerph191912630
14. Marwaha RK, Tandon N, Ganie MA, Kanwar R, Shivaprasad C, Sabharwal A, et al. Nationwide reference data for height, weight and body mass index of Indian schoolchildren. Natl Med J India. 2011;24(5):269–77.
15. Zellal A, Lemdani M, Djeddi N, Oudjhane K, Lalouche AB. Weight and height local growth charts of Algerian children and adolescents (6-18 years of age). J Pediatr Endocrinol Metab. 2016;29(4):393–402.
16. Durán P, Merker A, Briceño G, Colón E, Line D, Abad V, et al. Colombian reference growth curves for height, weight, body mass index and head circumference. Acta Pediatr. 2016;105(3):e116-25. http://dx.doi.org/10.1111/apa.13269
17. Baye K, Hirvonen K. Altitude and early child growth in 47 countries. Popul Environ. 2021;43(2):149–68.
18. Debebe, Wondwosen; Alem, Addis; Abebe, Melese Shenkut; Bihonegn, Mohammed Derso; Abdu, Hussen; et al. Higher altitude stunts children's physical growth: A systematic review and meta-analysis. Next Research. 2026; 3: 101059. https://doi.org/10.1016/j.nexres.2025.101059
19. Encuesta Nacional de Salud y Nutrición ENSANUT-ECU 2018. 2018;
20. Rivadeneira MF, Moncayo AL, Cóndor JD, Tello B, Buitrón J, Astudillo F, et al. High prevalence of chronic malnutrition in indigenous children under 5 years of age in Chimborazo-Ecuador: multicausal analysis of its determinants. BMC Public Health. 2022;22(1):1977. http://dx.doi.org/10.1186/s12889-022-14327-x
21. Ramírez-Luzuriaga MJ, Belmont P, Waters WF, Freire WB. Malnutrition inequalities in Ecuador: differences by wealth, education level and ethnicity. Public Health Nutr. 2020;23(S1):s59–67. http://dx.doi.org/10.1017/S1368980019002751
22. Cole TJ, Green PJ. Smoothing reference centile curves: the LMS method and penalized likelihood. Stat Med. 1992;11(10):1305–19. http://dx.doi.org/10.1002/sim.4780111005
23. INEC Base de datos antropométrica de niños y adolescentes ecuatorianos. Quito; 2021.
24. Tanner JM, Davies PS. Clinical longitudinal standards for height and height velocity for North American children. J Pediatr. 1985;107(3):317–29. http://dx.doi.org/10.1016/s0022-3476(85)80501-1
25. Abbassi V. Growth and normal puberty. Pediatrics. 1998;102(Supplement_3):507–11
26. Vargas-Zárate M, Becerra-Bulla F, Prieto-Suárez E, Bastidas-Báez V, Salazar-Rojas W. Percentiles de crecimiento para peso, talla e IMC en niños y adolescentes de 2 a 18 años de Huila, Colombia. Colombia Rev Fac Med. 2023;71(3).
27. Julian CG, Moore LG. Human genetic adaptation to high altitude: Evidence from the Andes. Genes (Basel). 2019;10(2):150. http://dx.doi.org/10.3390/genes10020150
28. Dubois L, Ohm Kyvik K, Girard M, Tatone-Tokuda F, Pérusse D, Hjelmborg J, et al. Genetic and environmental contributions to weight, height, and BMI from birth to 19 years of age: an international study of over 12,000 twin pairs. PLoS One. 2012;7(2):e30153. http://dx.doi.org/10.1371/journal.pone.0030153
29. Cossio-Bolaños M, Campos RG, Andruske CL, Flores AV, Luarte-Rocha C, Olivares PR, et al. Physical growth, biological age, and nutritional transitions of adolescents living at moderate altitudes in Peru. Int J Environ Res Public Health. 2015;12(10):12082–94. http://dx.doi.org/10.3390/ijerph121012082
30. Bozzola M, Meazza C. Growth velocity curves: What they are and how to use them. En: Handbook of Growth and Growth Monitoring in Health and Disease. New York, NY: Springer New York; 2012. p. 2999–3011.
31. Bogin B. The evolution of human brain and body growth patterns. En: Evolution of Nervous Systems. Elsevier; 2007. p. 337–45.
32. Long L, Hamdani SD, Hamdani SMZH, Zhuang J, Khurram H, Hadier SG. Establishing age- and sex-specific anthropometric growth references standards for South Punjab adolescents utilizing the LMS method: findings from the Pakistani population. Front Public Health. 2024;12:1417284. http://dx.doi.org/10.3389/fpubh.2024.1417284
Downloads
Published
Issue
Section
License
Copyright (c) 2026 FACSALUD-UNEMI

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Todos los artículos de la Revista FACSalud UNEMI son difundidos bajo licencia internacional Creative Commons Reconocimiento-NoComercial-SinObrasDerivadas 4.0.
Los autores mantienen los derechos de autor, y, por lo tanto, son libres de compartir, copiar, distribuir, ejecutar y comunicar públicamente la obra bajo las condiciones siguientes: Reconocer los créditos de la obra especificada por el autor e indicar si se realizaron cambios (puede hacerlo de cualquier forma razonable, pero no de una manera que sugiera que el autor respalda el uso que hace de su obra. No utilizar la obra para fines comerciales. En caso de remezcla, transformación o desarrollo, no puede distribuirse el material modificado.