Main complications post-treatment in patients with pituitary adenoma producing growth hormone
Keywords:
acromegaly, adenoma chromophobe, pituitary diseases, pituitary glandAbstract
Pituitary adenomas are benign intracranial tumors originating in the anterior portion of the hypophysis, thus constituting the most frequent pathology of alterations of the sella turcica in 90%. This type of tumors presents a great variety of clinical manifestations that will depend on the hormonal release, among them; galactorrhea due to excess prolactin, acromegaly or gigantism due to growth hormone alteration, Cushing's disease due to ACTH, hyperthyroidism due to TSH and sex hormone disorders FSH-LH. Acromegaly is a rare endocrinological disease characterized by a metabolic disorder of growth hormone and the consequent elevation of insulin-like growth factor, it also represents a great clinical challenge for endocrinologists and surgical for neurosurgeons, however in expert hands a remission of up to 80% can be achieved. In the present research work, a descriptive, retrospective, cross- sectional study was carried out in registered patients with a diagnosis of benign pituitary tumors and acromegaly who were admitted by the endocrinology, neurosurgery and neurology service at the Teodoro Maldonado Carbo Hospital during the period January 2011-December 2019. The result was a slight female predominance with 54%, the most frequent age was 65-67 years. Within the most frequent symptoms and clinical effects were headache, acral and facial alterations, cataloging the 21 % with Hardy ID. 88% of the patients received Octeotride, 45.5% received radiosurgery treatment with a recurrence rate of 41%.
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